Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders
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چکیده
منابع مشابه
Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders
NMDA receptor (NMDAR)-induced excitotoxicity is thought to contribute to the cell death associated with certain neurodegenerative diseases, stroke, epilepsy, and traumatic brain injury. Targeting NMDARs therapeutically is complicated by the fact that cell signaling downstream of their activation can promote cell survival and plasticity as well as excitotoxicity. However, research over the past ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2014
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2014.03.030